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Amino acids determining enzyme-substrate specificity in prokaryotic and eukaryotic protein kinases
The binding between a PK and its target is highly specific, despite the fact that many different PKs exhibit significant sequence and structure homology. There must be, then, specificity-determining residues (SDRs) that enable different PKs to recognize their unique substrate. Here we use and furthe...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153578/ https://ncbi.nlm.nih.gov/pubmed/12679523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0737647100 |
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