Amino acids determining enzyme-substrate specificity in prokaryotic and eukaryotic protein kinases
The binding between a PK and its target is highly specific, despite the fact that many different PKs exhibit significant sequence and structure homology. There must be, then, specificity-determining residues (SDRs) that enable different PKs to recognize their unique substrate. Here we use and furthe...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12679523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0737647100 |
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