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Statistical significance of protein structure prediction by threading

In this study, we estimate the statistical significance of structure prediction by threading. We introduce a single parameter ɛ that serves as a universal measure determining the probability that the best alignment is indeed a native-like analog. Parameter ɛ takes into account both length and compos...

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Detalhes bibliográficos
Main Authors: Mirny, Leonid A., Finkelstein, Alexey V., Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27644/
https://ncbi.nlm.nih.gov/pubmed/10954732
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