Evolution of the folding ability of proteins through functional selection
An evolutionary process is simulated with a simple spin-glass-like model of proteins to examine the origin of folding ability. At each generation, sequences are randomly mutated and subjected to a simulation of the folding process based on the model. According to the frequency of local configuration...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1997
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23457/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326608/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11324 |
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