Tailoring in vitro evolution for protein affinity or stability
We describe a rapid and general technology working entirely in vitro to evolve either the affinity or the stability of ligand-binding proteins, depending on the chosen selection pressure. Tailored in vitro selection strategies based on ribosome display were combined with in vitro diversification by...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011311398 |
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