Protein folding: How the mechanism of GroEL action is defined by kinetics
We propose a mechanism for the role of the bacterial chaperonin GroEL in folding proteins. The principal assumptions of the mechanism are (i) that many unfolded proteins bind to GroEL because GroEL preferentially binds small unstructured regions of the substrate protein, (ii) that substrate protein...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9159107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.11.5535 |
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