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Close identity of a pressure-stabilized intermediate with a kinetic intermediate in protein folding

Atomic detailed structural study of a transiently existing folding intermediate is severely limited because of its short life. In ubiquitin, we found that a pressure-stabilized equilibrium conformer shares a common structural feature with the proline-trapped kinetic intermediate found in a pulse-lab...

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Détails bibliographiques
Auteurs principaux: Kitahara, Ryo, Akasaka, Kazuyuki
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC152264/
https://ncbi.nlm.nih.gov/pubmed/12629216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0630309100
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