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Kinetics of chain motions within a protein-folding intermediate
Small proteins can fold remarkably rapidly, even in μs. What limits their rate of folding? The Engrailed homeodomain is a particularly well-characterized example, which folds ultrafast via an intermediate, I, of solved structure. It is a puzzle that the helix2-turn-helix3 motif of the 3-helix bundle...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009767/ https://ncbi.nlm.nih.gov/pubmed/21135210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011666107 |
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