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Malleability of folding intermediates in the homeodomain superfamily

Members of the homeodomain superfamily are three-helix bundle proteins whose second and third helices form a helix-turn-helix motif (HTH). Their folding mechanism slides from the ultrafast, three-state framework mechanism for the engrailed homeodomain (EnHD), in which the HTH motif is independently...

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Detalhes bibliográficos
Main Authors: Banachewicz, Wiktor, Religa, Tomasz L., Schaeffer, R. D., Daggett, Valerie, Fersht, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078393/
https://ncbi.nlm.nih.gov/pubmed/21422286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101752108
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