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Malleability of folding intermediates in the homeodomain superfamily

Members of the homeodomain superfamily are three-helix bundle proteins whose second and third helices form a helix-turn-helix motif (HTH). Their folding mechanism slides from the ultrafast, three-state framework mechanism for the engrailed homeodomain (EnHD), in which the HTH motif is independently...

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Библиографические подробности
Главные авторы: Banachewicz, Wiktor, Religa, Tomasz L., Schaeffer, R. D., Daggett, Valerie, Fersht, Alan R.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078393/
https://ncbi.nlm.nih.gov/pubmed/21422286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101752108
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