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A kinetically significant intermediate in the folding of barnase

A series of studies on the small protein barnase in the 1990s established it as a paradigm for protein folding in which there is a kinetically important intermediate. But, a recent study in PNAS claims that there are no stable intermediates on the folding pathway. I summarize the evidence that prove...

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Detalhes bibliográficos
Autor principal: Fersht, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18881/
https://ncbi.nlm.nih.gov/pubmed/11114199
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