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A protein folding pathway with multiple folding intermediates at atomic resolution
Using native-state hydrogen-exchange-directed protein engineering and multidimensional NMR, we determined the high-resolution structure (rms deviation, 1.1 Å) for an intermediate of the four-helix bundle protein: Rd-apocytochrome b(562). The intermediate has the N-terminal helix and a part of the C-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC555603/ https://ncbi.nlm.nih.gov/pubmed/15793003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501372102 |
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