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The high-resolution NMR structure of the early folding intermediate of the Thermus thermophilus ribonuclease H

Elucidation of the high-resolution structures of folding intermediates is a necessary but difficult step toward the ultimate understanding of the mechanism of protein folding. Here, using hydrogen exchange-directed protein engineering, we populated the folding intermediate of the T. thermophilus rib...

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Detalhes bibliográficos
Main Authors: Zhou, Zheng, Feng, Hanqiao, Ghirlando, Rodolfo, Bai, Yawen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628467/
https://ncbi.nlm.nih.gov/pubmed/18848567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.09.044
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