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The Folding Pathway of T4 Lysozyme: 1. An On-Pathway Hidden Folding Intermediate

T4 Lysozyme has two easily distinguishable but energetically coupled domains: the N- and C-terminal domains. In earlier studies, an amide hydrogen/deuterium exchange pulse-labeling experiment detected a stable sub-millisecond intermediate that accumulates before the rate-limiting transition state. I...

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Detalhes bibliográficos
Main Authors: Kato, Hidenori, Vu, Ngoc_Diep, Feng, Hanqiao, Zhou, Zheng, Bai, Yawen
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494531/
https://ncbi.nlm.nih.gov/pubmed/17097105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.10.048
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