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The Folding Pathway of T4 Lysozyme: 1. An On-Pathway Hidden Folding Intermediate
T4 Lysozyme has two easily distinguishable but energetically coupled domains: the N- and C-terminal domains. In earlier studies, an amide hydrogen/deuterium exchange pulse-labeling experiment detected a stable sub-millisecond intermediate that accumulates before the rate-limiting transition state. I...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494531/ https://ncbi.nlm.nih.gov/pubmed/17097105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.10.048 |
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