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Kinetic evidence of an on-pathway intermediate in the folding of lysozyme.

By means of a kinetic test, it was demonstrated that one of the folding intermediates (Ialpha) of hen lysozyme with alpha-domain folded and beta-domain unfolded is on the folding pathway under the classical definition. Ialpha folds to the native (N) state directly (unfolded (U) <==> Ialpha <...

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Détails bibliographiques
Auteur principal: Bai, Y.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144436/
https://ncbi.nlm.nih.gov/pubmed/10739262
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