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Absence of stable intermediates on the folding pathway of barnase

Barnase is one of the few protein models that has been studied extensively for protein folding. Previous studies led to the conclusion that barnase folds through a very stable submillisecond intermediate (≈3 kcal/mol). The structure of this intermediate was characterized intensively by using a prote...

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Detalhes bibliográficos
Main Authors: Takei, Jiro, Chu, Rui-Ai, Bai, Yawen
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27103/
https://ncbi.nlm.nih.gov/pubmed/10984513
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