The folding of GroEL-bound barnase as a model for chaperonin-mediated protein folding.
We have analyzed the pathway of folding of barnase bound to GroEL to resolve the controversy of whether proteins can fold while bound to chaperonins (GroEL or Cpn60) or fold only after their release into solution. Four phases in the folding were detected by rapid-reaction kinetic measurements of the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41687/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5326 |
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