GroEL-GroES-mediated protein folding requires an intact central cavity
The chaperonin GroEL is an oligomeric double ring structure that, together with the cochaperonin GroES, assists protein folding. Biochemical analyses indicate that folding occurs in a cis ternary complex in which substrate is sequestered within the GroEL central cavity underneath GroES. Recently, ho...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770457/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12163 |
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