Equilibria and kinetics of folding of gelsolin domain 2 and mutants involved in familial amyloidosis–Finnish type
Mutations D187N and D187Y in domain 2 of the actin-regulating protein gelsolin cause familial amyloidosis–Finnish type (FAF). We have constructed and expressed a recombinant version of gelsolin domain 2 that is sufficiently stable for kinetic and equilibrium measurements. The wild-type domain and th...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11247 |
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