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A protein folding pathway with multiple folding intermediates at atomic resolution

Using native-state hydrogen-exchange-directed protein engineering and multidimensional NMR, we determined the high-resolution structure (rms deviation, 1.1 Å) for an intermediate of the four-helix bundle protein: Rd-apocytochrome b(562). The intermediate has the N-terminal helix and a part of the C-...

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Bibliografske podrobnosti
Main Authors: Feng, Hanqiao, Zhou, Zheng, Bai, Yawen
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC555603/
https://ncbi.nlm.nih.gov/pubmed/15793003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501372102
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