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Granzyme B (GraB) Autonomously Crosses the Cell Membrane and Perforin Initiates Apoptosis and GraB Nuclear Localization

Granzyme B (GraB) induces apoptosis in the presence of perforin. Perforin polymerizes in the cell membrane to form a nonspecific ion pore, but it is not known where GraB acts to initiate the events that ultimately lead to apoptosis. It has been hypothesized that GraB enters the target cell through a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shi, Lianfa, Mai, Sabine, Israels, Sara, Browne, Kylie, Trapani, Joseph A., Greenberg, Arnold H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196167/
https://ncbi.nlm.nih.gov/pubmed/9120391
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