Llwytho...

Mitochondria-dependent and -independent Regulation of Granzyme B–induced Apoptosis

Granzyme B (GraB) is required for the efficient activation of apoptosis by cytotoxic T lymphocytes and natural killer cells. We find that GraB and perforin induce severe mitochondrial perturbation as evidenced by the release of cytochrome c into the cytosol and suppression of transmembrane potential...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: MacDonald, Glen, Shi, Lianfa, Velde, Christine Vande, Lieberman, Judy, Greenberg, Arnold H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887691/
https://ncbi.nlm.nih.gov/pubmed/9874570
Tagiau: Ychwanegu Tag
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