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Granzyme B (GraB) Autonomously Crosses the Cell Membrane and Perforin Initiates Apoptosis and GraB Nuclear Localization

Granzyme B (GraB) induces apoptosis in the presence of perforin. Perforin polymerizes in the cell membrane to form a nonspecific ion pore, but it is not known where GraB acts to initiate the events that ultimately lead to apoptosis. It has been hypothesized that GraB enters the target cell through a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Shi, Lianfa, Mai, Sabine, Israels, Sara, Browne, Kylie, Trapani, Joseph A., Greenberg, Arnold H.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 1997
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196167/
https://ncbi.nlm.nih.gov/pubmed/9120391
תגים: הוספת תג
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