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Phosphorylation-independent inhibition of parathyroid hormone receptor signaling by G protein-coupled receptor kinases

Homologous desensitization of G protein-coupled receptors is thought to occur in several steps: binding of G protein-coupled receptor kinases (GRKs) to receptors, receptor phosphorylation, kinase dissociation, and finally binding of β-arrestins to phosphorylated receptors. It generally is assumed th...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Dicker, Frank, Quitterer, Ursula, Winstel, Rainer, Honold, Konrad, Lohse, Martin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10318908/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.10.5476
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