Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases

The G protein-coupled receptor (GPCR) kinases (GRKs) phosphorylate and desensitize agonist-occupied GPCRs. GRK2-mediated receptor phosphorylation is preceded by the agonist-dependent membrane association of this enzyme. Previous in vitro studies with purified proteins have suggested that this transl...

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Detalhes bibliográficos
Main Authors: Daaka, Yehia, Pitcher, Julie A., Richardson, Mark, Stoffel, Robert H., Robishaw, Janet D., Lefkowitz, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20061/
https://ncbi.nlm.nih.gov/pubmed/9122168
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