Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds

Using both confocal immunofluorescence microscopy and biochemical approaches, we have examined the role of β-arrestins in the activation and targeting of extracellular signal-regulated kinase 2 (ERK2) following stimulation of angiotensin II type 1a receptors (AT1aR). In HEK-293 cells expressing hema...

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Detalhes bibliográficos
Main Authors: Luttrell, Louis M., Roudabush, Francine L., Choy, Eric W., Miller, William E., Field, Michael E., Pierce, Kristen L., Lefkowitz, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30158/
https://ncbi.nlm.nih.gov/pubmed/11226259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041604898
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