Phosphorylation-independent inhibition of parathyroid hormone receptor signaling by G protein-coupled receptor kinases

Homologous desensitization of G protein-coupled receptors is thought to occur in several steps: binding of G protein-coupled receptor kinases (GRKs) to receptors, receptor phosphorylation, kinase dissociation, and finally binding of β-arrestins to phosphorylated receptors. It generally is assumed th...

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Main Authors: Dicker, Frank, Quitterer, Ursula, Winstel, Rainer, Honold, Konrad, Lohse, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC21884/
https://ncbi.nlm.nih.gov/pubmed/10318908
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