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Reciprocal regulation of G(sα) by palmitate and the βγ subunit

Hormonal activation of G(s), the stimulatory regulator of adenylyl cyclase, promotes dissociation of α(s) from Gβγ, accelerates removal of covalently attached palmitate from the Gα subunit, and triggers release of a fraction of α(s) from the plasma membrane into the cytosol. To elucidate relations a...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Iiri, Taroh, Backlund, Peter S., Jones, Teresa L. Z., Wedegaertner, Philip B., Bourne, Henry R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26178/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962097/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14592
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