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Receptors induce chemotaxis by releasing the βγ subunit of G(i), not by activating G(q) or G(s)

Many chemoattractants cause chemotaxis of leukocytes by stimulating a structurally distinct class of G protein-coupled receptors. To identify receptor functions required for chemotaxis, we studied chemotaxis in HEK293 cells transfected with receptors for nonchemokine ligands or for interleukin 8 (IL...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Neptune, Enid R., Bourne, Henry R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25031/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405640/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14489
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