Receptors induce chemotaxis by releasing the βγ subunit of G(i), not by activating G(q) or G(s)
Many chemoattractants cause chemotaxis of leukocytes by stimulating a structurally distinct class of G protein-coupled receptors. To identify receptor functions required for chemotaxis, we studied chemotaxis in HEK293 cells transfected with receptors for nonchemokine ligands or for interleukin 8 (IL...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1997
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405640/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14489 |
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