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Direct interaction of Gβγ with a C-terminal Gβγ-binding domain of the Ca(2+) channel α(1) subunit is responsible for channel inhibition by G protein-coupled receptors
Several classes of voltage-gated Ca(2+) channels (VGCCs) are inhibited by G proteins activated by receptors for neurotransmitters and neuromodulatory peptides. Evidence has accumulated to indicate that for non-L-type Ca(2+) channels the executing arm of the activated G protein is its βγ dimer (Gβγ)....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences of the USA
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23172/ https://ncbi.nlm.nih.gov/pubmed/9238069 |
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