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Nuclear localization of pyrrole–imidazole polyamide–fluorescein conjugates in cell culture

A series of hairpin pyrrole–imidazole polyamide–fluorescein conjugates were synthesized and assayed for cellular localization. Thirteen cell lines, representing 11 human cancers, one human transformed kidney cell line, and one murine leukemia cell line, were treated with 5 μM polyamide–fluorescein c...

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Bibliografiske detaljer
Main Authors: Best, Timothy P., Edelson, Benjamin S., Nickols, Nicholas G., Dervan, Peter B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC218713/
https://ncbi.nlm.nih.gov/pubmed/14519850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2035074100
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