Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates

A pivotal step forward in chemical approaches to controlling gene expression is the development of sequence-specific DNA-binding molecules that can enter live cells and traffic to nuclei unaided. DNA-binding polyamides are a class of programmable, sequence-specific small molecules that have been sho...

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Publicado en:Nucleic Acids Res
Autores principales: Edelson, Benjamin S., Best, Timothy P., Olenyuk, Bogdan, Nickols, Nicholas G., Doss, Raymond M., Foister, Shane, Heckel, Alexander, Dervan, Peter B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2004
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Articles
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419610/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155849/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh609
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