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Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates

A pivotal step forward in chemical approaches to controlling gene expression is the development of sequence-specific DNA-binding molecules that can enter live cells and traffic to nuclei unaided. DNA-binding polyamides are a class of programmable, sequence-specific small molecules that have been sho...

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Main Authors: Edelson, Benjamin S., Best, Timothy P., Olenyuk, Bogdan, Nickols, Nicholas G., Doss, Raymond M., Foister, Shane, Heckel, Alexander, Dervan, Peter B.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC419610/
https://ncbi.nlm.nih.gov/pubmed/15155849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh609
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