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Nuclear localization of pyrrole–imidazole polyamide–fluorescein conjugates in cell culture

A series of hairpin pyrrole–imidazole polyamide–fluorescein conjugates were synthesized and assayed for cellular localization. Thirteen cell lines, representing 11 human cancers, one human transformed kidney cell line, and one murine leukemia cell line, were treated with 5 μM polyamide–fluorescein c...

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Detalles Bibliográficos
Main Authors: Best, Timothy P., Edelson, Benjamin S., Nickols, Nicholas G., Dervan, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC218713/
https://ncbi.nlm.nih.gov/pubmed/14519850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2035074100
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