Toll-like receptor-4 (TLR4) promotes the development of colitis-associated colorectal tumors

BACKGROUND AND AIM: Chronic inflammation is a risk factor for colon cancer in patients with ulcerative colitis (UC). The molecular mechanisms linking inflammation and colon carcinogenesis are incompletely understood. We tested the hypothesis that TLR4 is involved in tumorigenesis in the setting of c...

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Detalhes bibliográficos
Main Authors: Fukata, Masayuki, Chen, Anli, Vamadevan, Arunan S., Cohen, Jason, Breglio, Keith, Krishnareddy, Suneeta, Xu, Ruliang, Harpaz, Noam, Dannenberg, Andrew J., Subbaramaiah, Kotha, Cooper, Harry S., Itzkowitz, Steven H., Abreu, Maria T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180834/
https://ncbi.nlm.nih.gov/pubmed/18054559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.09.008
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