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The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease

Abnormal T cell responses to commensal bacteria are involved in the pathogenesis of inflammatory bowel disease (IBD). MyD88 is an essential signal transducer for TLRs in response to the microflora. We hypothesized that TLR signaling via MyD88 was important for effector T cell responses in the intest...

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Detalhes bibliográficos
Main Authors: Fukata, Masayuki, Breglio, Keith, Chen, Anli, Vamadevan, Arunan S., Goo, Tyralee, Hsu, David, Conduah, Daisy, Xu, Ruliang, Abreu, Maria T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828823/
https://ncbi.nlm.nih.gov/pubmed/18209086
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