The role of prostaglandin E(2 )(PGE (2)) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia

BACKGROUND: We have previously found that TLR4-deficient (TLR4-/-) mice demonstrate decreased expression of mucosal PGE (2 )and are protected against colitis-associated neoplasia. However, it is still unclear whether PGE (2 )is the central factor downstream of TLR4 signaling that promotes intestinal...

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Detalhes bibliográficos
Main Authors: Hernandez, Yasmin, Sotolongo, John, Breglio, Keith, Conduah, Daisy, Chen, Anli, Xu, Ruliang, Hsu, David, Ungaro, Ryan, Hayes, Lory A, Pastorini, Cristhine, Abreu, Maria T, Fukata, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912804/
https://ncbi.nlm.nih.gov/pubmed/20637112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-10-82
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