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Toll-like receptor-4 (TLR4) promotes the development of colitis-associated colorectal tumors

BACKGROUND AND AIM: Chronic inflammation is a risk factor for colon cancer in patients with ulcerative colitis (UC). The molecular mechanisms linking inflammation and colon carcinogenesis are incompletely understood. We tested the hypothesis that TLR4 is involved in tumorigenesis in the setting of c...

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Библиографические подробности
Главные авторы: Fukata, Masayuki, Chen, Anli, Vamadevan, Arunan S., Cohen, Jason, Breglio, Keith, Krishnareddy, Suneeta, Xu, Ruliang, Harpaz, Noam, Dannenberg, Andrew J., Subbaramaiah, Kotha, Cooper, Harry S., Itzkowitz, Steven H., Abreu, Maria T.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180834/
https://ncbi.nlm.nih.gov/pubmed/18054559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.09.008
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