Time-related increases in cardiac concentrations of doxorubicinol could interact with doxorubicin to depress myocardial contractile function.

Lignende værker

• Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol.
  af: Olson, R D, et al.
  Udgivet: (1988)
• Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein
  af: Asperen, J van, et al.
  Udgivet: (1999)
• Doxorubicin cardiomyopathy is associated with a decrease in calcium release channel of the sarcoplasmic reticulum in a chronic rabbit model.
  af: Dodd, D A, et al.
  Udgivet: (1993)
• Analysis of the Doxorubicin and Doxorubicinol in the Plasma of Breast Cancer Patients for Monitoring the Toxicity of Doxorubicin
  af: Harahap, Yahdiana, et al.
  Udgivet: (2020)
• Effect of the paclitaxel vehicle, Cremophor EL, on the pharmacokinetics of doxorubicin and doxorubicinol in mice.
  af: Webster, L. K., et al.
  Udgivet: (1996)