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Effect of the paclitaxel vehicle, Cremophor EL, on the pharmacokinetics of doxorubicin and doxorubicinol in mice.

The effect of the paclitaxel vehicle Cremophor on the pharmacokinetics of doxorubicin and doxorubicinol was studied in two groups of mice given intravenously either 2.5 ml kg-1 Cremophor or saline followed 5 min later by 10 mg kg-1 doxorubicin. In each group three mice were sacrificed at ten time po...

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Detalles Bibliográficos
Main Authors: Webster, L. K., Cosson, E. J., Stokes, K. H., Millward, M. J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074445/
https://ncbi.nlm.nih.gov/pubmed/8595168
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