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Population pharmacokinetics of orally administered paclitaxel formulated in Cremophor EL

AIM: The vehicle Cremophor EL (CrEL) has been shown to impair the absorption of paclitaxel by micellar entrapment of the drug in the gastrointestinal tract. The goal of this study was to develop a semimechanistic population pharmacokinetic model to study the influence of CrEL on the oral absorption...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: de Jonge, Milly E, Huitema, Alwin DR, Schellens, Jan HM, Rodenhuis, Sjoerd, Beijnen, Jos H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884789/
https://ncbi.nlm.nih.gov/pubmed/15752379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02325.x
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