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Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients
The non-linear plasma pharmacokinetics of paclitaxel in patients has been well established, however, the exact underlying mechanism remains to be elucidated. We have previously shown that the non-linear plasma pharmacokinetics of paclitaxel in mice results from Cremophor EL. To investigate whether C...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362856/ https://ncbi.nlm.nih.gov/pubmed/10496361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690696 |
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