Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol.

Doxorubicin (former generic name, adriamycin), a highly effective anticancer drug, produces cardiotoxicity, which limits its therapeutic potential. The mechanism of this cardiotoxicity has remained elusive. Our data suggest that this toxicity could involve doxorubicinol, the primary circulating meta...

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Dettagli Bibliografici
Autori principali: Olson, R D, Mushlin, P S, Brenner, D E, Fleischer, S, Cusack, B J, Chang, B K, Boucek, R J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC280258/
https://ncbi.nlm.nih.gov/pubmed/2897122
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