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Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol.

Doxorubicin (former generic name, adriamycin), a highly effective anticancer drug, produces cardiotoxicity, which limits its therapeutic potential. The mechanism of this cardiotoxicity has remained elusive. Our data suggest that this toxicity could involve doxorubicinol, the primary circulating meta...

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Detalhes bibliográficos
Main Authors: Olson, R D, Mushlin, P S, Brenner, D E, Fleischer, S, Cusack, B J, Chang, B K, Boucek, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280258/
https://ncbi.nlm.nih.gov/pubmed/2897122
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