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The Human Papillomavirus Type 16 E7 Oncoprotein Activates the Fanconi Anemia (FA) Pathway and Causes Accelerated Chromosomal Instability in FA Cells

Fanconi anemia (FA) patients have an increased risk for squamous cell carcinomas (SCCs) at sites of predilection for infection with high-risk human papillomavirus (HPV) types, including the oral cavity and the anogenital tract. We show here that activation of the FA pathway is a frequent event in ce...

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Autors principals: Spardy, Nicole, Duensing, Anette, Charles, Domonique, Haines, Nathan, Nakahara, Tomomi, Lambert, Paul F., Duensing, Stefan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169120/
https://ncbi.nlm.nih.gov/pubmed/17898070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01121-07
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