Centrosome Abnormalities and Genomic Instability by Episomal Expression of Human Papillomavirus Type 16 in Raft Cultures of Human Keratinocytes

Primary human keratinocytes with ectopic expression of high-risk human papillomavirus (HPV) E6 and E7 oncoproteins display abnormal centrosome numbers, multipolar mitoses, and aneusomy. However, it has not been explored whether these abnormalities can occur in cells containing HPV episomes where E6...

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Détails bibliographiques
Auteurs principaux: Duensing, Stefan, Duensing, Anette, Flores, Elsa R., Do, Anh, Lambert, Paul F., Münger, Karl
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2001
Sujets:
Transformation and Oncogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC115006/
https://ncbi.nlm.nih.gov/pubmed/11462043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7712-7716.2001
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