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The Human Papillomavirus Type 16 E7 Oncoprotein Activates the Fanconi Anemia (FA) Pathway and Causes Accelerated Chromosomal Instability in FA Cells

Fanconi anemia (FA) patients have an increased risk for squamous cell carcinomas (SCCs) at sites of predilection for infection with high-risk human papillomavirus (HPV) types, including the oral cavity and the anogenital tract. We show here that activation of the FA pathway is a frequent event in ce...

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Detalhes bibliográficos
Main Authors: Spardy, Nicole, Duensing, Anette, Charles, Domonique, Haines, Nathan, Nakahara, Tomomi, Lambert, Paul F., Duensing, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169120/
https://ncbi.nlm.nih.gov/pubmed/17898070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01121-07
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