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Genomic Instability and Cancer: Lessons Learned from Human Papillomaviruses

High-risk HPV E6 and E7 oncoproteins cooperate to subvert critical host cell cycle checkpoint control mechanisms in order to promote viral genome replication. This results not only in aberrant proliferation but also in host cellular changes that can promote genomic instability. The HPV-16 E7 oncopro...

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Detalhes bibliográficos
Main Authors: Korzeniewski, Nina, Spardy, Nicole, Duensing, Anette, Duensing, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046211/
https://ncbi.nlm.nih.gov/pubmed/21075512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.10.013
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