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Genomic Instability and Cancer: Lessons Learned from Human Papillomaviruses
High-risk HPV E6 and E7 oncoproteins cooperate to subvert critical host cell cycle checkpoint control mechanisms in order to promote viral genome replication. This results not only in aberrant proliferation but also in host cellular changes that can promote genomic instability. The HPV-16 E7 oncopro...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046211/ https://ncbi.nlm.nih.gov/pubmed/21075512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.10.013 |
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